L'Alberta agira à titre de promoteur du projet d'oléoduc devant le Bureau des grands projets.

Québec bonifiera également le soutien financier de la relève en agriculture.

Karine Boivin Roy se dit réceptive aux inquiétudes quant au guichet unique pour le logement abordable.

Paul St-Pierre Plamondon sera le premier chef de parti à discuter de questions internationales avec l’organisme.

La Centrale des syndicats du Québec (CSQ) a déposé devant la Cour supérieure, vendredi, sa contestation de la nouvelle loi sur la gouvernance et la transparence syndicales.

Entrer ou sortir de Montréal s’annonce difficile cet été. Pas moins de 9 des 16 ponts ou tunnels reliant l’île seront en chantier au cours des prochains mois, parmi les 52 chantiers majeurs annoncés vendredi pour l’été 2026.

ATLANTA, May 15, 2026 (GLOBE NEWSWIRE) — Countdown, a nonprofit accelerating mitochondrial science and medicine across the full spectrum of human health, announced a new research grant awarded to Dr. Elias Adriaenssens at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria.  The funding will support a groundbreaking project titled From Hypoxia to Therapy: Unlocking Mitochondrial Clearance Pathways for Disease Treatment, focused on understanding how cells identify, clear, and renew damaged mitochondria, the tiny structures responsible for producing the energy every cell in the body needs to survive and function.  Mitochondrial dysfunction is a foundational and shared driver across many of today’s most pressing health challenges, from rare and chronic disease to neurodegeneration, metabolic disease, and age-related decline. Yet despite mitochondria’s central role in human health, many of the underlying cellular quality-control mechanisms remain poorly understood.  One of the most promising emerging areas in mitochondrial medicine is hypoxia therapy, the controlled reduction of oxygen exposure to activate protective cellular pathways. Hypoxia has emerged as a potential therapeutic strategy across a broad range of conditions and diseases, including primary mitochondrial diseases, Parkinson’s, ischemic injury, and age-related decline. Yet despite its therapeutic promise, chronic systemic hypoxia is difficult to implement clinically, requiring prolonged exposure to tightly controlled low-oxygen environments that are not realistically compatible with everyday life. Moreover, systemic hypoxia can induce widespread stress responses and undesirable biological adaptations across multiple tissues. Dr. Adriaenssens’ research seeks to solve one of the field’s most important challenges: how to isolate the beneficial mitochondrial effects of hypoxia without exposing patients to its dangerous systemic consequences. Every cell has a built-in system for removing damaged mitochondria and maintaining cellular health. When that process breaks down, damaged mitochondria can accumulate inside cells, triggering inflammation, dysfunction, and tissue damage throughout the body.  The project focuses on a poorly understood mitochondrial quality-control pathway, which appears to act as a brake on the cell’s mitochondrial renewal system. The research aims to identify how to selectively activate protective mitochondrial clearance pathways associated with hypoxia, without triggering the dangerous systemic effects of whole-body hypoxia.  The long-term goal is to help lay the foundation for therapies that could mimic the protective effects of hypoxia through patient-compatible treatments, eliminating  the impractical and potentially dangerous need for continuous low-oxygen exposure or hypoxic chambers.  What makes this research especially significant is that cells contain multiple pathways for removing damaged mitochondria, yet science has only deeply understood one of them. By uncovering alternative mitochondrial clearance mechanisms, this research could open new therapeutic possibilities across a wide range of diseases and conditions where mitochondrial dysfunction plays a central role. The findings may also help advance one of medicine’s most promising emerging frontiers: mitochondrial transplantation. While early studies suggest transplanted mitochondria could help rescue damaged tissues, one of the biggest barriers remains that healthy mitochondria are often recognized and destroyed by the cell before they can successfully integrate and function. Understanding these newly identified quality-control pathways may help overcome that challenge and make mitochondrial transplantation more durable and effective.  “Countdown funds research at a cellular level, the shared biology beneath conditions that most organizations address in isolation,” said Mitzi Solomon, Founder and President of Countdown. “This grant exemplifies the broad-reaching implications of mitochondrial research, as the molecular insight Dr. Adriaenssens is pursuing could ultimately benefit patients across rare disease, neurodegeneration, heart disease, transplantation, and aging — all at once.”  “For patients with mitochondrial dysfunction, the options today are still largely supportive. This research moves us toward something genuinely different, a way to selectively activate the cell’s own renewal machinery without the side effects of systemic approaches,” said Dr. Elias Adriaenssens, Research Institute of Molecular Pathology (IMP), Vienna. “Countdown’s investment gives us the runway to do the work that makes rational drug design possible.”  The grant is made in honor of Countdown board member Gerry King, whose commitment to advancing mitochondrial research while living with Parkinson’s disease reflects the urgency and importance of this work.  “We are all overwhelmed by the endless requests for support across countless causes and organizations,” said Gerry King, Countdown Board Member. “I made the decision to place my commitment behind Countdown because of its uncompromising passion to uncover the root causes beneath diseases affecting all walks of life. Mitochondrial dysfunction impacts all of us, and I believe mitochondrial research has the potential to change not only the lives of people living with Parkinson’s disease, but the future of human health itself. My support of Countdown and this mission will continue until meaningful breakthroughs — and ultimately cures — are found.”   Founded on the belief that mitochondrial health is not a niche concern but a window into nearly every major disease challenge of our time, Countdown funds research across six interconnected pillars — Early Detection & Precision Diagnostics, Women’s Health & Hormonal Longevity, Primary Mitochondrial & Rare Genetic Disease, Chronic Disease & Aging, Brain Energy & Cognitive Resilience, and Advanced Therapeutics & Frontier Innovation. The organization unites scientists, clinicians, philanthropists, and industry partners to move the field forward faster, accelerating discoveries that shape a future where mitochondrial science is central to how we understand, treat, and prevent disease. About Countdown  Countdown is a nonprofit focused on accelerating mitochondrial science and medicine across the full spectrum of human health to improve how people feel, function, and age. By focusing on mitochondria — the shared biological network underlying many of the most pressing diseases of our time — Countdown is driving a more integrated approach to accelerating scientific breakthroughs that transform how we understand, prevent, and treat disease at its source. We fund research, expand awareness, and unite scientists, clinicians, philanthropists, industry leaders, and visionary brands to drive real-world impact. Join the Countdown to change the future of health.  For more information, visit www.joincountdown.org  About Elias Adriaenssens Elias Adriaenssens is a postdoctoral researcher in the laboratory of Tim Clausen at the Research Institute of Molecular Pathology (IMP) at the Vienna BioCenter. He joined the Vienna BioCenter in 2019 as a postdoctoral researcher at the neighbouring Max Perutz Labs. Adriaenssens completed his PhD in molecular biology at the University of Antwerp in Belgium. He also holds a Master’s degree in pharmacology from the University of Oxford (2014), as well as undergraduate and Master’s degrees in biochemistry from the University of Antwerp. He has received several awards and honours, including a Medical Research Council (MRC) Studentship Award (2013) / Wolfson College High Profile Achievement Award (2014); a Rotary Hope-in-Head Grant (2019); and a Marie Skłodowska-Curie Actions (MSCA) Postdoctoral Fellowship. About the IMP The Research Institute of Molecular Pathology (IMP) in Vienna is a basic life science research institute largely sponsored by Boehringer Ingelheim. With over 220 scientists from 40 countries, the IMP is committed to scientific discovery of fundamental molecular and cellular mechanisms underlying complex biological phenomena. The IMP is part of the Vienna BioCenter, one of Europe’s most dynamic life science hubs with 2,800 staff members from over 80 countries in seven research institutions, two universities, and 42 biotech companies. www.imp.ac.at, www.viennabiocenter.org   Follow Countdown on Instagram, Facebook, LinkedIn, X and YouTube Contact:Mitzi Solomon, Founder and PresidentMitzi@JoinCountdown.org | +1 (917) 715-2381 The post Countdown Grant Explores How Cells Remove Damaged Mitochondria — Opening New Possibilities Across Parkinson’s, Chronic Disease, Rare Disease, and Aging appeared first on Montreal Gazette.

After more than a decade, the Anse-à-l’Orme branch has finally begun shuttling its first passengers. On Friday, reporters and dignitaries got the first rides on the branch, which spans over four stations between Pointe-Claire and Ste-Anne-de-Bellevue. The entire branch covers 14 kilometres, and will get West Islanders to downtown’s McGill station in 33 minutes from the Anse-à-l’Orme station and 22 minutes from Des Sources. “It’s going to be a real game-changer for the people of the West Island,” said Carl Corbel, director of REM operations for CDPQ Infra. “We will offer 20 hours per day of operations with more than 80 trains passing from 5:30 in the morning to 1:30 at night, so going to the Bell Centre in 35 minutes is really going to be amazing for people around here.” Unlike the Deux-Montagnes and South Shore branches, this segment of the REM is serving a transit-starved area where residents have had few mass-transit options to get downtown effectively. For that reason, CDPQ Infra directors believe growth on this branch will be slow but steady. The REM has already recorded an average of 78,000 daily riders on the Deux-Montagnes and Brossard branches. Planners believe adding the West Island and airport branches will allow it to achieve its goal of 150,000 daily riders. The airport branch, with a stop in St-Laurent’s Technoparc, is expected to begin running by the end of next year. Editor’s Picks With limited parking, access to REM's Anse-à-l'Orme branch expected to be difficult Here's how the REM's new Deux-Montagnes branch could transform life across Greater Montreal What you need to know about the REM's Deux-Montagnes branch opening this weekend To celebrate the opening of the branch, the REM will be free to ride from the four new REM stations: Anse-à-l’Orme, Kirkland, Fairview-Pointe-Claire and Des Sources. Those stations will have free entry on Saturday and Sunday from 9 a.m. to 6 p.m., while the rest of the network will remain open to paying clientele. The Anse-à-l’Orme branch will remain open between 6 p.m. and 1:30 a.m., but anyone boarding at those times will have to pay a fare. On the island of Montreal, riding the REM costs the same as paying for a regular fare on the STM. The branch’s opening is the realization of a lobbying effort that began with a group called le Train de l’Ouest, which lobbied for a modern, frequent rail service in the West Island. “It’s a big day for the West Island,” said Clifford Lincoln, who headed the lobbying effort for several years. “I think some people in the south will still need the Exo Vaudreuil-Hudson Line, so I hope it keeps going. With the parking issues, I don’t see them using the REM as much. But I think the REM will be very well supported by (residents of the area).” Among the biggest concerns of politicians and would-be transit users of the new branch is the lack of parking and difficult accessibility of some of the stations, which are located along congested highways with few parking spots available. On Friday, CDPQ Infra said it has heard the concerns, so it made a deal with Cadillac Fairview to provide 300 parking spots at the Fairview Pointe-Claire mall across from the station. Initial plans for the station didn’t include any public parking. “We just signed the deal yesterday,” Julien Hurel, vice-president of REM for CDPQ Infra said on the train as it was passing by the shopping centre. The new branch will now have more than 1,000 parking spots near the four stations, if you include the 200 spaces reserved exclusively for Kirkland residents at the Kirkland station. The largest parking lot is around the Des Sources station, with more than 400 spaces. Hurel said it is possible to add more parking spaces around the stations if the demand merits it. The addition of the branch now makes the REM the world’s largest automated light-rail network, spanning 62 kilometres across 23 stations. Initially announced in 2016, the REM began construction in 2019 with a goal of opening in 2021. The Brossard to Central Station branch opened in the summer of 2023, while the Deux-Montagnes branch began last November. CDPQ Infra estimates the cost for building the entire network will reach more than $9 billion. Jason Magder You'll often see Jason Magder donning a hard hat and florescent vest at a local construction site. As The Gazette's transportation reporter for more than a decade, he has seen the new Champlain Bridge built, the old one demolished and followed the ups and downs of the city's transit system. He has been covering news in Montreal for 25 years. The post REM Anse-à-l’Orme branch opens to the public this weekend appeared first on Montreal Gazette.

Ontario's Ministry of Health says it is now testing 10 asymptomatic people with connections to a hantavirus-stricken cruise, a shift from government remarks made earlier this week.

Ontario's top court has dismissed an appeal filed by former fashion mogul Peter Nygard, upholding his sexual assault convictions and prison sentence.

Ukrainian President Volodymyr Zelenskyy promised retribution against Russia on Friday after laying red roses at the rubble of a Kyiv apartment building where a Russian missile strike killed 24 people, including three children.

Israel and Lebanon have agreed to a 45-day extension of their ceasefire after another round of talks in Washington, the U.S. State Department said Friday.

Multiple weather systems are bringing a mixed bag of weather across Canada for the long weekend, with snow and wind in the Prairies and above-seasonal temperatures across Ontario.

A new report commissioned by the Wine Growers of Canada says the sector could be worth an extra $3.7 billion if Canadians drank more homegrown wine.

The US president says he wants Beijing and Taipei to "cool down" tensions over the self-governing island.

There were plenty of choreographed ceremonies but no trade breakthroughs after the two-day visit.

World Health Organization has reiterated that the risk of hantavirus spreading is 'low'.

Trip comes as court rules separatists did not follow proper procedure in collecting referendum signatures.